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Article

Interleukin-1 system gene polymorphisms are associated with fat mass in young men.

The Journal of clinical endocrinology and metabolism - 1 Jul 2006

Strandberg Louise, Lorentzon Mattias, Hellqvist Asa, Nilsson Staffan, Wallenius Ville, Ohlsson Claes, Jansson John-Olov

Abstract excerpt

CONTEXT: There is growing evidence for interactions between the regulation of body fat and the immune system. Studies of knockout mice indicate that IL-1 has an antiobesity effect. OBJECTIVE: The objective of the study was to investigate our hypothesis that common polymorphisms of the IL-1 system, which are associated with IL-1 activity, also are associated with fat mass. DESIGN, SETTING, AND STUDY SUBJECTS: The...

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Identifiers

PMID: 16636119
DOI: 10.1210/jc.2005-2786

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