Article
Lipoprotein receptor-related protein 1 variants and dietary fatty acids: meta-analysis of European origin and African American studies.
International journal of obesity (2005) - 1 Sept 2013
Smith C E, Ngwa J, Tanaka T, Qi Q, Wojczynski M K, Lemaitre R N, Anderson J S, Manichaikul A, Mikkilä V, van Rooij F J A, Ye Z, Bandinelli S, Frazier-Wood A C, Houston D K, Hu F, Langenberg C, McKeown N M, Mozaffarian D, North K E, Viikari J, Zillikens M C, Djoussé L, Hofman A, Kähönen M, Kabagambe E K, Loos R J F, Saylor G B, Forouhi N G, Liu Y, Mukamal K J, Chen Y-D I, Tsai M Y, Uitterlinden A G, Raitakari O, van Duijn C M, Arnett D K, Borecki I B, Cupples L A, Ferrucci L, Kritchevsky S B, Lehtimäki T, Qi Lu, Rotter J I, Siscovick D S, Wareham N J, Witteman J C M, Ordovás J M, Nettleton J A
Abstract excerpt
OBJECTIVE: Low-density lipoprotein-related receptor protein 1 (LRP1) is a multi-functional endocytic receptor and signaling molecule that is expressed in adipose and the hypothalamus. Evidence for a role of LRP1 in adiposity is accumulating from animal and in vitro models, but data from human studies are limited. The study objectives were to evaluate (i) relationships between LRP1 genotype and anthropometric...
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