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Article

Effect of natural polymorphisms in the HIV-1 CRF02_AG protease on protease inhibitor hypersusceptibility.

Antimicrobial agents and chemotherapy - 1 May 2012

Santos André F A, Tebit Denis M, Lalonde Matthew S, Abecasis Ana B, Ratcliff Annette, Camacho Ricardo J, Diaz Ricardo S, Herchenröder Ottmar, Soares Marcelo A, Arts Eric J

Abstract excerpt

Hypersusceptibility (HS) to inhibition by different antiretroviral drugs (ARVs) among diverse HIV-infected individuals may be a misnomer because clinical response to treatment is evaluated in relation to subtype B infections while drug susceptibility of the infecting virus, regardless of subtype, is compared to a subtype B HIV-1 laboratory strain (NL4-3 or IIIB). Mounting evidence suggests that HS to different...

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Identifiers

PMID: 22330918
DOI: 10.1128/AAC.06079-11
PMCID: PMC3346603

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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