Article
K65R and Y181C are less prevalent in HAART-experienced HIV-1 subtype A patients.
AIDS (London, England) - 4 Nov 2005
Gupta Ravindra K, Chrystie Ian L, O'Shea Siobhan, Mullen Jane E, Kulasegaram Ranjababu, Tong Cheuk Y W
Abstract excerpt
The vast majority of HIV-1 infections globally are caused by subtype A or C, although little is known about their drug resistance profiles. We found that HAART-experienced patients infected with subtype A had a lower prevalence of K65R and Y181C than those with subtypes B or C, despite similar exposure to antiretroviral agents that select for these mutations. If confirmed, this information may be important in the...
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