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Article

Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence.

AIDS reviews - 1 Jan 2000

Martínez-Cajas Jorge L, Pant-Pai Nitika, Klein Marina B, Wainberg Mark A

Abstract excerpt

The genetic diversity of HIV-1 has required its classification into types and subtypes. There is controversy as to how and to what extent genetic diversity may affect the emergence of antiretroviral drug resistance in HIV-1 subtypes other than B. To better understand the impact of genetic diversity (represented by different HIV-1 subtypes) on resistance to reverse transcriptase and protease inhibitor drugs, a...

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PMID: 19092977

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