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The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strains

2020-01-31

Abstract excerpt

<h4>Background: </h4> The rate of S68G mutation in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase has increased and is closely related to the K65R mutation among CRF01_AE-infected patients who failed treatment. We aimed to explore the temporal association of S68G and K65R mutations and disclose the role of the former on susceptibility to nucleotide/nucleoside reverse transcriptase inhibitor (NRT...

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Literature Corpus work
001261a0-367a-555f-a4bb-0d1cbf703cea
DOI
10.21203/rs.2.15317/v4
Open publication

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The S68G polymorphism is a compensatory mutation associated with the drug resistance mutation K65R in CRF01_AE strainsDOI 10.21203/rs.2.15317/v4
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