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Article

Protease polymorphisms in HIV-1 subtype CRF01_AE represent selection by antiretroviral therapy and host immune pressure.

AIDS (London, England) - 28 Jan 2010

Manosuthi Weerawat, Butler David M, Pérez-Santiago Josué, Poon Art Fy, Pillai Satish K, Mehta Sanjay R, Pacold Mary E, Richman Douglas D, Pond Sergei Kosakovsky, Smith Davey M

Abstract excerpt

BACKGROUND: Most of our knowledge about how antiretrovirals and host immune responses influence the HIV-1 protease gene is derived from studies of subtype B virus. We investigated the effect of protease resistance-associated mutations (PRAMs) and population-based HLA haplotype frequencies on poly...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20009919
DOI: 10.1097/QAD.0b013e3283350eef
PMCID: PMC2913588

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20009919-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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