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Article

[Methods for determination of HIV tropism and their clinical use].

Enfermedades infecciosas y microbiologia clinica - 1 Dec 2011

Gutiérrez Félix, Rodríguez Juan Carlos, García Federico, Poveda Eva

Abstract excerpt

Determination of HIV-1 tropism is mandatory before using CCR5 antagonists in clinical practice. One drug of this class, maraviroc, has been approved for the treatment of HIV infection. The phenotypic assay, TrofileTM, was clinically validated in the clinical development program of maraviroc and has been widely used to select candidates for maraviroc therapy. Phenotypic tests, however, have the disadvantage of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22305669
DOI: 10.1016/S0213-005X(11)70043-X

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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