Article
[Methods for determining viral tropism: genotype and phenotype tests].
Enfermedades infecciosas y microbiologia clinica - 1 Oct 2008
Perez-Olmeda Mayte, Poveda Eva
Abstract excerpt
The recent approval of the first CCR5 antagonist, Maraviroc (MVC, Celsentri), with specific antiviral activity against R5-tropic virus variants has generated the need for studies to determine the viral tropism in all those patient candidates for starting treatment with this new drug. Although genotyping methods appear to be the most useful tool due to its speed and simplicity, in the case of viral tropism,...
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