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Article

Genetic and genomic analysis of hyperlipidemia, obesity and diabetes using (C57BL/6J × TALLYHO/JngJ) F2 mice.

BMC genomics - 19 Dec 2010

Stewart Taryn P, Kim Hyoung Yon, Saxton Arnold M, Kim Jung Han

Abstract excerpt

BACKGROUND: Type 2 diabetes (T2D) is the most common form of diabetes in humans and is closely associated with dyslipidemia and obesity that magnifies the mortality and morbidity related to T2D. The genetic contribution to human T2D and related metabolic disorders is evident, and mostly follows polygenic inheritance. The TALLYHO/JngJ (TH) mice are a polygenic model for T2D characterized by obesity,...

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Identifiers

PMID: 21167066
DOI: 10.1186/1471-2164-11-713
PMCID: PMC3022919

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Genetic and genomic analysis of hyperlipidemia, obesity and diabetes using (C57BL/6J × TALLYHO/JngJ) F2 mice.PMID 21167066Read ↗

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Whole genome sequence analysis of the TALLYHO/Jng mouse.Semantic proximity Read ↗

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