Article
Mapping and Congenic Dissection of Genetic Loci Contributing to Hyperglycemia and Dyslipidemia in Mice.
PloS one - 1 Jan 2016
Shi Weibin, Wang Qian, Choi Wonseok, Li Jing
Abstract excerpt
BACKGROUND: Patients with dyslipidemia have an increased risk of developing type 2 diabetes, and diabetic patients often have dyslipidemia. Potential genetic connections of fasting plasma glucose with plasma lipid profile were evaluated using hyperlipidemic mice. METHODS: 225 male F2 mice were generated from BALB/cJ (BALB) and SM/J(SM) Apoe-deficient (Apoe-/-) mice and fed a Western diet for 5 weeks. Fasting...
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