Article
Effects of angiotensin receptor blockers on endothelial nitric oxide release: the role of eNOS variants.
British journal of clinical pharmacology - 1 Jul 2012
Mason R Preston, Jacob Robert F, Kubant Ruslan, Jacoby Adam, Louka Febee, Corbalan J Jose, Malinski Tadeusz
Abstract excerpt
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT: • Angiotensin II receptor blockers improve endothelial cell-dependent vasodilation in patients with hypertension through suppression of angiotensin II type 1 receptors but may have additional and differential effects on endothelial nitric oxide synthase (eNOS) function. WHAT THIS STUDY ADDS: • The key finding from this study is that angiotensin II receptor blockers (ARBs)...
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