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Article

eNOS and BDKRB2 genotypes affect the antihypertensive responses to enalapril.

European journal of clinical pharmacology - 1 Feb 2013

Silva P S, Fontana V, Luizon M R, Lacchini R, Silva W A, Biagi C, Tanus-Santos J E

Abstract excerpt

PURPOSE: The antihypertensive effect of angiotensin-converting enzyme inhibitors (ACEi) is attributed partially to increased nitric oxide bioavailability. It is possible that functional polymorphisms in endothelial nitric oxide synthase (eNOS) and bradykinin receptor B2 (BDKRB2) genes may affect the antihypertensive response to enalapril. METHODS: We evaluated 106 hypertensive patients treated only with enalapril...

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Share to Angiotensin-Converting Enzyme Inhibitors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

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Share to Nitric Oxide Synthase Type III

Share to Polymorphism, Genetic

Share to Receptor, Bradykinin B2

Source

Identifiers

PMID: 22706620
DOI: 10.1007/s00228-012-1326-2

Genes

BDKRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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