Article
ENU-based phenotype-driven screening.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2012
Ripoll Vera M, Kong Philip L, Potter Paul K
Abstract excerpt
Deciphering the contribution of individual genes and in turn pathways to cellular processes can be complicated and is often based on prior knowledge or assumptions of gene function. Phenotype-driven mutagenesis screens based around n-ethyl-n-nitrosurea (ENU) have been successful in a wide range of physiological systems in identifying novel genes that contribute to a given phenotype. Here, we describe...
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