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Article

Mouse ENU mutagenesis.

Human molecular genetics - 1 Jan 1999

Justice M J, Noveroske J K, Weber J S, Zheng B, Bradley A

Abstract excerpt

The progress of human genome sequencing is driving genetic approaches to define gene function. Strategies such as gene traps and chemical mutagenesis will soon generate a large mutant mouse resource. Point mutations induced by N -ethyl- N -nitrosourea (ENU) provide a unique mutant resource because they: (i) reflect the consequences of single gene change independent of position effects; (ii) provide a...

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PMID: 10469849
DOI: 10.1093/hmg/8.10.1955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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