Article
Mouse mutagenesis-systematic studies of mammalian gene function.
Human molecular genetics - 1 Jan 1998
Brown S D, Nolan P M
Abstract excerpt
The mouse will play a pivotal role in mammalian gene function studies as we enter the post-genomics era. The challenge is to develop systematic, genome-wide mutagenesis approaches to the study of gene function. The current mouse mutant resource has been an important source of human genetic disease models. However, despite an apparently large catalogue of mouse mutations, we have access to mutations at only a...
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