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Article

Genetic gating of human fear learning and extinction: possible implications for gene-environment interaction in anxiety disorder.

Psychological science - 1 Feb 2009

Lonsdorf Tina B, Weike Almut I, Nikamo Pernilla, Schalling Martin, Hamm Alfons O, Ohman Arne

Abstract excerpt

Pavlovian fear conditioning is a widely used model of the acquisition and extinction of fear. Neural findings suggest that the amygdala is the core structure for fear acquisition, whereas prefrontal cortical areas are given pivotal roles in fear extinction. Forty-eight volunteers participated in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19175757
DOI: 10.1111/j.1467-9280.2009.02280.x

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19175757-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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