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Article

5-HTTLPR-environment interplay and its effects on neural reactivity in adolescents.

NeuroImage - 15 Nov 2012

Walsh Nicholas D, Dalgleish Tim, Dunn Valerie J, Abbott Rosemary, St Clair Michelle C, Owens Matthew, Fairchild Graeme, Kerslake William S, Hiscox Lucy V, Passamonti Luca, Ewbank Michael, Ban Maria, Calder Andrew J, Goodyer Ian M

Abstract excerpt

It is not known how 5-HTTLPR genotype x childhood adversity (CA) interactions that are associated with an increased risk for affective disorders in population studies operate at the neural systems level. We hypothesized that healthy adolescents at increased genetic and environmental risk for developing mood disorders (depression and anxiety) would demonstrate increased amygdala reactivity to emotional stimuli...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23034517
DOI: 10.1016/j.neuroimage.2012.07.067
PMCID: PMC3480648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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