Article
A two-stage association study identifies methyl-CpG-binding domain protein 2 gene polymorphisms as candidates for breast cancer susceptibility.
European journal of human genetics : EJHG - 1 Jun 2012
Sapkota Yadav, Robson Paula, Lai Raymond, Cass Carol E, Mackey John R, Damaraju Sambasivarao
Abstract excerpt
Genome-wide association studies for breast cancer have identified over 40 single-nucleotide polymorphisms (SNPs), a subset of which remains statistically significant after genome-wide correction. Improved strategies for mining of genome-wide association data have been suggested to address heritable component of genetic risk in breast cancer. In this study, we attempted a two-stage association design using markers...
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