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Article

Associations between single nucleotide polymorphisms in double-stranded DNA repair pathway genes and familial breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2009

Sehl Mary E, Langer Lucy R, Papp Jeanette C, Kwan Lorna, Seldon Joyce L, Arellano Geovanni, Reiss Jean, Reed Elaine F, Dandekar Sugandha, Korin Yael, Sinsheimer Janet S, Zhang Zuo-Feng, Ganz Patricia A

Abstract excerpt

PURPOSE: DNA damage recognition and repair play a major role in risk for breast cancer. We investigated 104 single nucleotide polymorphisms (SNP) in 17 genes whose protein products are involved in double-stranded break repair (DSBR). EXPERIMENTAL DESIGN: We used a case-control design. Both the ca...

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Identifiers

PMID: 19276285
DOI: 10.1158/1078-0432.CCR-08-1417
PMCID: PMC2778342

Genes

BRCA1
BRCA2
RAD21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-19276285-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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