Article
Fine-mapping of the 6q25 locus identifies a novel SNP associated with breast cancer risk in African-American women.
Carcinogenesis - 1 Feb 2013
Ruiz-Narváez Edward A, Rosenberg Lynn, Yao Song, Rotimi Charles N, Cupples Adrienne L, Bandera Elisa V, Ambrosone Christine B, Adams-Campbell Lucile L, Palmer Julie R
Abstract excerpt
The rs2046210 single nucleotide polymorphism (SNP) in the 6q25.1 region was identified in a breast cancer genome-wide association study of Chinese women. The SNP has been replicated in European ancestry populations, but replication efforts have failed in African ancestry populations. We evaluated a total of 13 tagging SNPs in the linkage disequilibrium block around rs2046210 in a case-control study of breast...
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