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Article

SNP-SNP interactions in breast cancer susceptibility.

BMC cancer - 3 May 2006

Onay Venüs Ummiye, Briollais Laurent, Knight Julia A, Shi Ellen, Wang Yuanyuan, Wells Sean, Li Hong, Rajendram Isaac, Andrulis Irene L, Ozcelik Hilmi

Abstract excerpt

BACKGROUND: Breast cancer predisposition genes identified to date (e.g., BRCA1 and BRCA2) are responsible for less than 5% of all breast cancer cases. Many studies have shown that the cancer risks associated with individual commonly occurring single nucleotide polymorphisms (SNPs) are incremental. However, polygenic models suggest that multiple commonly occurring low to modestly penetrant SNPs of cancer related...

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Source

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Identifiers

PMID: 16672066
DOI: 10.1186/1471-2407-6-114
PMCID: PMC1522021

Genes

COMT
BARD1
BRCA1
BRCA2
CCND1
GSTP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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