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Article

Common genetic variants in sex hormone pathway genes and papillary thyroid cancer risk.

Thyroid : official journal of the American Thyroid Association - 1 Feb 2012

Schonfeld Sara J, Neta Gila, Sturgis Erich M, Pfeiffer Ruth M, Hutchinson Amy A, Xu Li, Wheeler William, Guénel Pascal, Rajaraman Preetha, de Vathaire Florent, Ron Elaine, Tucker Margaret A, Chanock Stephen J, Sigurdson Alice J, Brenner Alina V

Abstract excerpt

BACKGROUND: Hormonal differences are hypothesized to contribute to the approximately ≥2-fold higher thyroid cancer incidence rates among women compared with men worldwide. Although thyroid cancer cells express estrogen receptors and estrogen has a proliferative effect on papillary thyroid cancer (PTC) cells in vitro, epidemiologic studies have not found clear associations between thyroid cancer and female...

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Identifiers

PMID: 22224819
DOI: 10.1089/thy.2011.0309
PMCID: PMC3271376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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