Article
Common obesity-related genetic variants and papillary thyroid cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Dec 2012
Kitahara Cari M, Neta Gila, Pfeiffer Ruth M, Kwon Deukwoo, Xu Li, Freedman Neal D, Hutchinson Amy A, Chanock Stephen J, Sturgis Erich M, Sigurdson Alice J, Brenner Alina V
Abstract excerpt
BACKGROUND: Epidemiologic studies have shown consistent associations between obesity and increased thyroid cancer risk, but, to date, no studies have investigated the relationship between thyroid cancer risk and obesity-related single-nucleotide polymorphisms (SNP). METHODS: We evaluated 575 tag SNPs in 23 obesity-related gene regions in a case-control study of 341 incident papillary thyroid cancer (PTC) cases...
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