Article
Common genetic variants in the 8q24 region and risk of papillary thyroid cancer.
The Laryngoscope - 1 May 2012
Neta Gila, Yu Chu-Ling, Brenner Alina, Gu Fangyi, Hutchinson Amy, Pfeiffer Ruth, Sturgis Erich M, Xu Li, Linet Martha S, Alexander Bruce H, Chanock Stephen, Sigurdson Alice J
Abstract excerpt
OBJECTIVES/HYPOTHESIS: Single nucleotide polymorphisms (SNPs) in the 8q24 chromosomal region identified from genome-wide scans have been associated with the risk of several cancers, including breast (rs1562430), prostate (rs1447295), and colon (rs6983267). A genome-wide scan in 26 families with papillary thyroid cancer (PTC) also found susceptibility loci in 8q24, supporting a closer evaluation of this...
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