Article
Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 4 Jan 2012
Maison Stéphane F, Liu Xiao-Ping, Eatock Ruth Anne, Sibley David R, Grandy David K, Liberman M Charles
Abstract excerpt
Pharmacological studies suggest that dopamine release from lateral olivocochlear efferent neurons suppresses spontaneous and sound-evoked activity in cochlear nerve fibers and helps control noise-induced excitotoxicity; however, the literature on cochlear expression and localization of dopamine receptors is contradictory. To better characterize cochlear dopaminergic signaling, we studied receptor localization...
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