Article
C1ql1 is expressed in adult outer hair cells of the cochlea in a tonotopic gradient.
PloS one - 1 Jan 2021
Biswas Joyshree, Pijewski Robert S, Makol Rohit, Miramontes Tania G, Thompson Brianna L, Kresic Lyndsay C, Burghard Alice L, Oliver Douglas L, Martinelli David C
Abstract excerpt
Hearing depends on the transduction of sounds into neural signals by the inner hair cells of the cochlea. Cochleae also have outer hair cells with unique electromotile properties that increase auditory sensitivity, but they are particularly susceptible to damage by intense noise exposure, ototoxic drugs, and aging. Although the outer hair cells have synapses on afferent neurons that project to the brain, the...
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