Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Localization of synucleins in the mammalian cochlea.

Journal of the Association for Research in Otolaryngology : JARO - 1 Dec 2008

Akil O, Weber C M, Park S N, Ninkina N, Buchman V, Lustig L R

Abstract excerpt

Synucleins are widely expressed synaptic proteins within the central nervous system that have been implicated in such neurodegenerative disorders as Parkinson's disease. In this study, an initial characterization of all three synucleins, alpha-, beta-, and gamma-synuclein, within the cochlea was undertaken. Reverse transcriptase-polymerase chain reaction (PCR) demonstrated all three synuclein mRNA species within...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to Cochlea
Share to Evoked Potentials, Auditory, Brain Stem

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hair Cells, Auditory, Inner

Share to Hair Cells, Auditory, Outer

Share to Otoacoustic Emissions, Spontaneous

Share to Receptors, Nicotinic

Share to Synucleins

Source

Open in PubMed Open full text

Identifiers

PMID: 18665422
DOI: 10.1007/s10162-008-0134-y
PMCID: PMC2580813

Genes

ABR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localization of synucleins in the mammalian cochlea.PMID 18665422Read ↗

Neurons Expressing the Highest Levels of γ-Synuclein Are Unaffected by Targeted Inactivation of the GeneSemantic proximity Read ↗

Hypokinesia and Reduced Dopamine Levels in Zebrafish Lacking β- and γ1-SynucleinsSemantic proximity Read ↗

A mutation in synaptojanin 2 causes progressive hearing loss in the ENU-mutagenised mouse strain Mozart.Semantic proximity Read ↗

Gamma synuclein: Subcellular localization in neuronal and non‐neuronal cells and effect on signal transductionSemantic proximity Read ↗

Mouse models of age-related mitochondrial neurosensory hearing loss.Semantic proximity Read ↗

Silent Spread: Olfactory Bulb α-Synuclein Seeding in Wild-Type Mice Drives Pathology and Transient Neuroinflammation While Sparing FunctionSemantic proximity Read ↗

Discovery and characterization of three novel synuclein genes in zebrafishSemantic proximity Read ↗

β-Actin and γ-Actin Are Each Dispensable for Auditory Hair Cell Development But Required for Stereocilia MaintenanceSemantic proximity Read ↗

Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31.Semantic proximity Read ↗

α-Synuclein in the olfactory system of a mouse model of Parkinson's disease: correlation with olfactory projections.Semantic proximity Read ↗

Dopaminergic signaling in the cochlea: receptor expression patterns and deletion phenotypes.Semantic proximity Read ↗

Functional role of GABAergic innervation of the cochlea: phenotypic analysis of mice lacking GABA(A) receptor subunits alpha 1, alpha 2, alpha 5, alpha 6, beta 2, beta 3, or delta.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.