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Article

Aberrant retinal projections in congenitally deaf mice: how are phenotypic characteristics specified in development and evolution?

The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology - 1 Nov 2005

Hunt Deborah L, King Bryan, Kahn Dianna M, Yamoah Ebenezer N, Shull Gary E, Krubitzer Leah

Abstract excerpt

The contribution of sensory input to the formation of sensory system-specific (sensoritopic) connections of the thalamus and midbrain was investigated using mice lacking the Na+-K+-2Cl- cotransporter (NKCC1) or the plasma membrane Ca2+-ATPase isoform2 (PMCA2). Because these mice are congenitally deaf, the developing nervous system has no exposure to sensory-driven neural activity from the auditory system. Here we...

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PMID: 16200647
DOI: 10.1002/ar.a.20251

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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