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Article

Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers.

Molecular neurobiology - 1 Dec 2020

Filova Iva, Dvorakova Martina, Bohuslavova Romana, Pavlinek Adam, Elliott Karen L, Vochyanova Simona, Fritzsch Bernd, Pavlinkova Gabriela

Abstract excerpt

Ear development requires the transcription factors ATOH1 for hair cell differentiation and NEUROD1 for sensory neuron development. In addition, NEUROD1 negatively regulates Atoh1 gene expression. As we previously showed that deletion of the Neurod1 gene in the cochlea results in axon guidance defects and excessive peripheral innervation of the sensory epithelium, we hypothesized that some of the innervation...

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Identifiers

PMID: 32880858
DOI: 10.1007/s12035-020-02092-0
PMCID: PMC7547283

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers.PMID 32880858Read ↗

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