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Article

The concentration of cyclosporine metabolites is significantly lower in kidney transplant recipients with diabetes mellitus.

Therapeutic drug monitoring - 1 Feb 2012

Akhlaghi Fatemeh, Dostalek Miroslav, Falck Pål, Mendonza Anisha E, Amundsen Rune, Gohh Reginald Y, Asberg Anders

Abstract excerpt

BACKGROUND: Diabetes mellitus is prevalent among kidney transplant recipients. The activity of drug metabolizing enzymes or transporters may be altered by diabetes leading to changes in the concentration of parent drug or metabolites. This study was aimed to characterize the effect of diabetes on the concentration of cyclosporine (CsA) and metabolites. METHODS: Concentration-time profiles of CsA and metabolites...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22210099
DOI: 10.1097/FTD.0b013e318241ac71

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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