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Article

Evaluating de novo locus-disease discoveries in GWAS using the signal-to-noise ratio.

AMIA ... Annual Symposium proceedings. AMIA Symposium - 1 Jan 2011

Jiang Xia, Barmada M Michael, Becich Michael J

Abstract excerpt

A genome-wide association study (GWAS) involves examining representative SNPs obtained using high throughput technologies. A GWAS data set can entail a million SNPs and may soon entail many millions. In a GWAS researchers often investigate the correlation of each SNP with a disease. With so many hypotheses, it is not straightforward how to interpret the results. Strategies include using the Bonferroni correction...

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PMID: 22195117
PMCID: PMC3243170

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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