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Article

A bayesian method for evaluating and discovering disease loci associations.

PloS one - 1 Jan 2011

Jiang Xia, Barmada M Michael, Cooper Gregory F, Becich Michael J

Abstract excerpt

BACKGROUND: A genome-wide association study (GWAS) typically involves examining representative SNPs in individuals from some population. A GWAS data set can concern a million SNPs and may soon concern billions. Researchers investigate the association of each SNP individually with a disease, and it is becoming increasingly commonplace to also analyze multi-SNP associations. Techniques for handling so many...

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PMID: 21853025
DOI: 10.1371/journal.pone.0022075
PMCID: PMC3154195

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