Article
Bayesian GWAS with Structured and Non-Local Priors.
Bioinformatics (Oxford, England) - 1 Jan 2020
Kaplan Adam, Lock Eric F, Fiecas Mark
Abstract excerpt
MOTIVATION: The flexibility of a Bayesian framework is promising for GWAS, but current approaches can benefit from more informative prior models. We introduce a novel Bayesian approach to GWAS, called Structured and Non-Local Priors (SNLPs) GWAS, that improves over existing methods in two important ways. First, we describe a model that allows for a marker's gene-parent membership and other characteristics to...
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