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Article

Estimating the number of true discoveries in genome-wide association studies.

Statistics in medicine - 20 May 2012

Lee Woojoo, Gusnanto A, Salim A, Magnusson P, Sim Xueling, Tai E S, Pawitan Y

Abstract excerpt

Recent genome-wide association studies have reported the discoveries of genetic variants of small to moderate effects. However, most studies of complex diseases face a great challenge because the number of significant variants is less than what is required to explain the disease heritability. A new approach is needed to recognize all potential discoveries in the data. In this paper, we present a practical...

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Identifiers

PMID: 21987428
DOI: 10.1002/sim.4391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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