Article
LEAP: biomarker inference through learning and evaluating association patterns.
Genetic epidemiology - 1 Mar 2015
Jiang Xia, Neapolitan Richard E
Abstract excerpt
Single nucleotide polymorphism (SNP) high-dimensional datasets are available from Genome Wide Association Studies (GWAS). Such data provide researchers opportunities to investigate the complex genetic basis of diseases. Much of genetic risk might be due to undiscovered epistatic interactions, which are interactions in which combination of several genes affect disease. Research aimed at discovering interacting...
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