Article
Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells.
Free radical biology & medicine - 1 Feb 2012
Pazmandi Kitti, Magyarics Zoltan, Boldogh Istvan, Csillag Aniko, Rajnavolgyi Eva, Bacsi Attila
Abstract excerpt
Under normal conditions, plasmacytoid dendritic cells (pDCs) are located in peripheral lymphoid organs or circulate in the blood, from where they can migrate to sites of infection or inflammation. In inflamed tissues, pDCs can be exposed to elevated levels of reactive oxygen species produced by inflammatory cells and we presume that oxidative stress could affect the cellular responses of pDCs to...
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