Article
Reactive oxygen species activate human peripheral blood dendritic cells.
Free radical biology & medicine - 1 Jan 1999
Rutault K, Alderman C, Chain B M, Katz D R
Abstract excerpt
This study investigates the effects of hydrogen peroxide, a potent oxygen free radical donor, on the phenotype and function of dendritic cells differentiated from peripheral blood precursors. We report that hydrogen peroxide induces an up-regulation of several dendritic cell surface markers invol...
Topics
- Acetylcysteine
- Antigens, CD
- B7-2 Antigen
- CD40 Antigens
- Cell Communication
- Dendritic Cells
- Free Radical Scavengers
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Hydrogen Peroxide
- In Vitro Techniques
- Lymphocyte Activation
- Membrane Glycoproteins
- Oxidative Stress
- Phenotype
- Reactive Oxygen Species
- T-Lymphocytes
