Article
Reactive oxygen species activate human peripheral blood dendritic cells.
Free radical biology & medicine - 1 Jan 1999
Rutault K, Alderman C, Chain B M, Katz D R
Abstract excerpt
This study investigates the effects of hydrogen peroxide, a potent oxygen free radical donor, on the phenotype and function of dendritic cells differentiated from peripheral blood precursors. We report that hydrogen peroxide induces an up-regulation of several dendritic cell surface markers involved in interaction with T cells, including MHC Class II molecules (DQ and DR) and the co-stimulatory molecules CD40 and...
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