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Article

Influence of genetic polymorphisms in cytochrome P450 oxidoreductase on the variability in stable warfarin maintenance dose in Han Chinese.

European journal of clinical pharmacology - 1 Nov 2016

Zeng Wu-Tao, Xu Qing, Li Cheng-Hsun, Chen Wei-Yan, Sun Xiu-Ting, Wang Xiang, Yang Yi-Ying, Shi Hui, Yang Zhi-Sheng

Abstract excerpt

PURPOSE: The aim of this study was to investigate whether any of the single-nucleotide polymorphisms (SNPs) in the POR gene were significantly associated with CYP activity and expression, and could contribute to the total variability in stable warfarin maintenance doses in Han Chinese. METHODS: A total of 408 patients treated at the First Affiliated Hospital of Sun Yat-Sen University were eligible for the study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27488389
DOI: 10.1007/s00228-016-2098-x

Genes

POR
VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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