Article
[Impact of six genetic polymorphisms on Warfarin maintenance dose variation in Chinese Han population].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2014
Lou Ying, Han Lulu, Li Yan, Zhang Xiaoxing, Liu Zhihong, Tang Min, Yu Haiwen, Wang Wei, Xu Jianping, Liu Hong, Li Yishi
Abstract excerpt
OBJECTIVE: To evaluate the effect of VKORC1, CYP2C9, GGCX, PROC, EPHX1 and CYP4F2 gene polymorphisms on Warfarin maintenance dose variation in Chinese Han Population. METHODS: Four hundred eighty-eight patients with prosthetic heart valves, atrial fibrillation or pulmonary thromboembolism and achieved stable Warfarin dose were enrolled. TaqMan probe or direct sequencing were used to genotype Y9VKORC1, CYP2C9,...
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