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Article

Influence of CYP4F2 genotype on warfarin dose requirement-a systematic review and meta-analysis.

Thrombosis research - 1 Jul 2012

Liang Ruijuan, Wang Chunling, Zhao Hong, Huang Jie, Hu Dayi, Sun Yihong

Abstract excerpt

INTRODUCTION: Warfarin is a commonly used oral anticoagulant and the dosage is individually adjusted on the basis of the international normalized ratio (INR) monitoring. It is well known that gene polymorphisms of CytochromeP450 (CYP) 2C9 gene and the vitamin K epoxide reductase complex 1 (VKORC1) were significantly associated with warfarin dose. However, the association between Cytochrome P450 4F2 (CYP4F2)...

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Source

Identifiers

PMID: 22192158
DOI: 10.1016/j.thromres.2011.11.043

Genes

CYP4F2
VKORC1

Variants

rs2108622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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