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Article

Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer.

Breast cancer research : BCR - 1 Jan 2011

Staaf Johan, Jönsson Göran, Ringnér Markus, Baldetorp Bo, Borg Ake

Abstract excerpt

INTRODUCTION: Human epidermal growth factor receptor 2 (HER2)-amplified breast cancer represents a clinically well-defined subgroup due to availability of targeted treatment. However, HER2-amplified tumors have been shown to be heterogeneous at the genomic level by genome-wide microarray analyses, pointing towards a need of further investigations for identification of recurrent copy number alterations and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22169037
DOI: 10.1186/bcr3075
PMCID: PMC3326571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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