Article

Copy Number–Based Chromosomal Instability Ex-Score Predicts Breast Cancer Malignancy

2026-02-26

Abstract excerpt

<title>Abstract</title> <p>Background Histological grade (HG) is an essential pathological factor of malignancy in breast cancer, but its evaluation remains partly subjective and affected by interobserver variability. Because genomic instability reflects intrinsic tumor aggressiveness, we hypothesized that genome-wide copy number variation (CNV) profiles in primary tumors may serve as an objective indicator of m...

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Literature Corpus work: c5b79b67-7354-5fc5-aa39-21d4c6689712
DOI: 10.21203/rs.3.rs-8925909/v1

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