Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer.

Genes, chromosomes & cancer - 1 Nov 2006

Bergamaschi Anna, Kim Young H, Wang Pei, Sørlie Therese, Hernandez-Boussard Tina, Lonning Per E, Tibshirani Robert, Børresen-Dale Anne-Lise, Pollack Jonathan R

Abstract excerpt

Breast cancer is a leading cause of cancer-death among women, where the clinicopathological features of tumors are used to prognosticate and guide therapy. DNA copy number alterations (CNAs), which occur frequently in breast cancer and define key pathogenetic events, are also potentially useful p...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Aberrations
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Gene Expression Regulation, Neoplastic

Share to Neoplasm Proteins

Share to Nucleic Acid Hybridization

Share to Oligonucleotide Array Sequence Analysis

Share to Survival Rate

Source

Identifiers

PMID: 16897746
DOI: 10.1002/gcc.20366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16897746-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distinct patterns of DNA copy number alteration are associated with different clinicopathological features and gene-expression subtypes of breast cancer.PMID 16897746Read ↗

DNA amplifications in breast cancer: genotypic-phenotypic correlations.Semantic proximity Read ↗

Copy Number Alteration Signatures As Biomarkers in Cancer: A ReviewSemantic proximity Read ↗

Luminal breast epithelial cells from wildtype and <i>BRCA</i> mutation carriers harbor copy number alterations commonly associated with breast cancerSemantic proximity Read ↗

Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumorsSemantic proximity Read ↗

Landscape of somatic allelic imbalances and copy number alterations in HER2-amplified breast cancer.Semantic proximity Read ↗

Genome-wide copy number alterations in subtypes of invasive breast cancers in young white and African American womenSemantic proximity Read ↗

Identification of Breast Cancer Subtype-Specific Biomarkers by Integrating Copy Number Alterations and Gene Expression ProfilesSemantic proximity Read ↗

Genomic instability in breast cancer: pathogenesis and clinical implications.Semantic proximity Read ↗

Luminal breast epithelial cells of BRCA1 or BRCA2 mutation carriers and noncarriers harbor common breast cancer copy number alterations.Semantic proximity Read ↗

Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug responseSemantic proximity Read ↗

Copy number alterations in metastatic and early breast tumours: prognostic and acquired biomarkers of resistance to CDK4/6 inhibitors.Semantic proximity Read ↗

Loss of chromosome cytoband 13q14.2 orchestrates breast cancer pathogenesis and drug responseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.