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Article

Genetic polymorphisms of the Wnt receptor LRP5 are differentially associated with trochanteric and cervical hip fractures.

Calcified tissue international - 1 Feb 2012

Riancho Javier, García-Ibarbia Carmen, Pérez-Núñez María I, Alonso María A, Díaz Teresa, Pérez-Castrillón José L, Riancho José A

Abstract excerpt

Epidemiological studies suggest that cervical and trochanteric hip fractures have different pathogenesis. We tested the hypothesis that genetic factors have different influences on both types of fractures. Ten polymorphisms of genes known to play an important role in skeletal homeostasis [estrogen receptor alpha (ESR1), aromatase (CYP19A1), type I collagen (COL1A1), and lipoprotein receptor-related protein 5...

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Source

Identifiers

PMID: 22167346
DOI: 10.1007/s00223-011-9557-2

Genes

LRP5
ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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