Article
Haplotypes of intron 4 of the estrogen receptor alpha gene and hip fractures: a replication study in Caucasians.
BMC medical genetics - 28 Jan 2010
Velasco Javier, Hernández José L, Pérez-Castrillón José L, Zarrabeitia María T, Alonso María A, González-Macías Jesús, Riancho José A
Abstract excerpt
BACKGROUND: Despite their great impact, few genetic association studies have used hip fractures as an endpoint. However, the association of two polymorphisms on intron 4 of estrogen receptor alpha (ESR1) with hip fractures was recently reported in a Chinese population. The aim of this study was to investigate whether such association is also present in Caucasians. METHODS: We analyzed those two SNPs and another...
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