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Article

Association of the A1330V and V667M polymorphisms of LRP5 with bone mineral density in Greek peri- and postmenopausal women.

Maturitas - 1 Oct 2011

Markatseli Anastasia E, Hatzi Elissavet, Bouba Ioanna, Georgiou Ioannis, Challa Anna, Tigas Stelios, Tsatsoulis Agathocles

Abstract excerpt

UNLABELLED: Wnt signaling through low-density lipoprotein receptor-related protein 5 (LRP5) is an important determinant of bone mass regulation. OBJECTIVE: To explore the influence of two LRP5 single nucleotide polymorphisms (SNPs) A1330V and V667M on bone mineral density (BMD) and serum levels of osteoprotegerin (OPG), receptor activator of nuclear factor-κB ligand (RANKL) and bone metabolic markers in a Greek...

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Source

Identifiers

PMID: 21840657
DOI: 10.1016/j.maturitas.2011.07.016

Genes

LRP5

Provenance

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Related research

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