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Article

Wnt receptors, bone mass, and fractures: gene-wide association analysis of LRP5 and LRP6 polymorphisms with replication.

European journal of endocrinology - 1 Jan 2011

Riancho José A, Olmos José M, Pineda Begoña, García-Ibarbia Carmen, Pérez-Núñez María I, Nan Daniel N, Velasco Javier, Cano Antonio, García-Pérez Miguel A, Zarrabeitia María T, González-Macías Jesús

Abstract excerpt

OBJECTIVE: Genes explaining the susceptibility to osteoporosis have not been fully elucidated. Our objective was to explore the association of polymorphisms capturing common variations of the lipoprotein receptor-related protein (LRP) 5 and 6 genes, encoding two Wnt receptors, with femoral neck bone mineral density (BMD) and osteoporotic fractures of the spine and the hip. DESIGN: Cross-sectional, case-control,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fractures, Bone

Share to LDL-Receptor Related Proteins

Share to Low Density Lipoprotein Receptor-Related Protein-5

Share to Low Density Lipoprotein Receptor-Related Protein-6

Share to Osteoporosis, Postmenopausal

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Source

Identifiers

PMID: 20926594
DOI: 10.1530/EJE-10-0582

Genes

LRP5
LRP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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