Article
Strong effect of SNP rs4988300 of the LRP5 gene on bone phenotype of Caucasian postmenopausal women.
Journal of bone and mineral metabolism - 1 Jan 2016
Horváth Péter, Balla Bernadett, Kósa János P, Tóbiás Bálint, Szili Balázs, Kirschner Gyöngyi, Győri Gabriella, Kató Karina, Lakatos Péter, Takács István
Abstract excerpt
The purpose of this study was to identify relationships between single nucleotide polymorphisms (SNPs) in the genes of the Wnt pathway and bone mineral density (BMD) of postmenopausal women. We chose this pathway due to its importance in bone metabolism that was underlined in several studies. DNA samples of 932 Hungarian postmenopausal women were studied. First, their BMD values at different sites (spine, total...
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