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Article

LRP4 association to bone properties and fracture and interaction with genes in the Wnt- and BMP signaling pathways.

Bone - 1 Sept 2011

Kumar Jitender, Swanberg Maria, McGuigan Fiona, Callreus Mattias, Gerdhem Paul, Akesson Kristina

Abstract excerpt

Osteoporosis is a common complex disorder in postmenopausal women leading to changes in the micro-architecture of bone and increased risk of fracture. Members of the low-density lipoprotein receptor-related protein (LRP) gene family regulates the development and physiology of bone through the Wnt/β-catenin (Wnt) pathway that in turn cross-talks with the bone morphogenetic protein (BMP) pathway. In two cohorts of...

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Source

Identifiers

PMID: 21645651
DOI: 10.1016/j.bone.2011.05.018

Genes

LRP4
LRP5
BMP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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